Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Trifluoromethyl)cyclopropanamine hydrochloride → HCID 51029816, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Trifluoromethyl)cyclopropanamine hydrochloride | HCID 11651196 | — |
| 반응물 | (4AS,5aS)-1-(pyrazin-2-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid | HCID 68004668 | — |
| 생성물 | HCID 51029816 | HCID 51029816 | — |
반응 단계
The title compound was prepared in a manner similar to that described in Method UU using Intermediate 4 and 1-(trifluoromethyl)cyclopropanamine hydrochloride. LCMS m/z=350.2 [M+H]+; 1H NMR (400 MHz, CDCl3) δ 0.47 (td, J=4.6, 3.2 Hz, 1H), 1.23-1.29 (m, 3H), 1.39-1.43 (m, 2H), 2.27-2.33 (m, 1H), 2.74-2.80 (m, 1H), 2.94 (d, J=16.8 Hz, 1H), 3.02 (dd, J=16.7 and 6.2 Hz, 1H), 7.31 (s, 1H), 8.42 (dd, J=2.5 and 1.5 Hz, 1H), 8.52 (d, J=2.5 Hz, 1H), 9.26 (d, J=1.4 Hz, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08778950B2 |
| 출처 데이터셋 | uspto-grants-2014_07 |
| ORD ID | ord-4db32058edd14d30ac7c19d95f29c042 |
| 출처 메모 | uspto-grants-2014_07 |