HCID 71114832, compound → HCID 71136990, compound

Participants

Reaction Steps

4-(6,7-Dihydro-1H-indazol-4-yl)-2-fluoro-benzonitrile (0.102 g, 0.43 mmol) 5% Pd/C wt/wt % (0.04 g) is added to MeOH (5.0 mL) and the mixture is stirred under 45-35 psi of hydrogen for 3 hours. The mixture is filtered through a plug of diatomaceous earth and concentrated to dryness. The residue is purified by silica gel chromatography eluting with 1:1 hexanes/ethyl acetate to give the title compound (0.021 g, 18%). ES/MS m/z 242 (M+H).

Provenance & Evidence