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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1624378Generated: October 31, 2026

1-[4'-(4-Bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester → 1-{4'-[3-Methyl-4-(4-phenyl-[1,2,3]triazol-1-ylmethyl)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1624378

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4'-(4-Bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66577199—
Reactant4-phenyl-1H-1,2,3-triazoleHCID 178420127—
Product1-{4'-[3-Methyl-4-(4-phenyl-[1,2,3]triazol-1-ylmethyl)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66579266—

Reaction Steps

Prepared according to the procedure described in Example 6, Step 3, using 1-[4′-(4-bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 4-phenyl-1H-1,2,3-triazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778983B2
Source datasetuspto-grants-2014_07
ORD IDord-ec0bc2a86b714058ab06ad7a4863fad3
Source noteuspto-grants-2014_07