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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1624390Generated: October 27, 2026

5-Phenyl-1H-tetrazole → 1-{4'-[3-Methyl-4-(5-phenyl-tetrazol-2-ylmethyl)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1624390

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Phenyl-1H-tetrazoleHCID 87425—
Reactant1-[4'-(4-Bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66577199—
Product1-{4'-[3-Methyl-4-(5-phenyl-tetrazol-2-ylmethyl)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66577770—

Reaction Steps

Prepared according to the procedure described in Example 6, Step 3, using 1-[4′-(4-bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 5-phenyl-2H-tetrazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778983B2
Source datasetuspto-grants-2014_07
ORD IDord-5ae05312c965442aa2f7296fcf5a0e4c
Source noteuspto-grants-2014_07