1,3,4-Oxadiazole, 2-phenyl- → [5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-(5-phenyl-[1,3,4]oxadiazol-2-yl)-methanol

HRID 1624410Notes

Reaction equation

HRID 1624410 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]=[O:15])=[CH:4][CH:3]=1.[C:16]1([C:22]2[O:23][CH:24]=[N:25][N:26]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[CH:14]([C:24]2[O:23][C:22]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[N:26][N:25]=2)[OH:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 132171,3,4-Oxadiazole, 2-phenyl-HCID 821337925-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde

Product 1

HCID 66577813[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-(5-phenyl-[1,3,4]oxadiazol-2-yl)-methanol

Procedure

Prepared according to the procedure described in Example 19, Step 1, using 5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde and 2-phenyl-[1,3,4]oxadiazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c9eb57044f6149b487c3a68c991e50ce
Source dataset
uspto-grants-2014_07
Patent number
US08778983B2

Reaction notes

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