HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dibromopyridine → 2-Bromo-6-(3-(trifluoromethyl)phenyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dibromopyridine | HCID 12274 | — |
| Reactant | 4,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane | HCID 2760604 | — |
| Catalyst | Bis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloropalladium;iron(2+) | HCID 178418228 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | 2-Bromo-6-(3-(trifluoromethyl)phenyl)pyridine | HCID 45788377 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 10, using 4,4,5,5-tetramethyl-2-(3-trifluoromethyl-phenyl)-[1,3,2]dioxaborolane and 2,6-dibromo-pyridine. Additionally, (1,1′-bis(diphenylphosphino)ferrocene)-dichloropalladium(II) was used as the catalyst in place of tetrakis(triphenylphosphine)palladium(0).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778983B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-eba60b539a4949eda93054a10dbcf57c |
| Source note | uspto-grants-2014_07 |