Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1624454Generated: November 3, 2026

Phenylboronic Acid → 2-Bromo-6-phenylpyrazine

https://huagongshe.com/reaction/1624454

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylboronic AcidHCID 66827—
Reactant2,6-DibromopyrazineHCID 20361700—
CatalystBis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloropalladium;iron(2+)HCID 178418228—
CatalystHCID 178418397HCID 178418397—
Product2-Bromo-6-phenylpyrazineHCID 45788327—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 10, using 2,6-dibromo-pyrazine and phenylboronic acid. Additionally, (1,1′-bis(diphenylphosphino)ferrocene)-dichloropalladium(II) was used as the catalyst in place of tetrakis(triphenylphosphine)palladium(0).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778983B2
Source datasetuspto-grants-2014_07
ORD IDord-59beaf11ed4b4fc79f480036f064fb4d
Source noteuspto-grants-2014_07