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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1624474Generated: October 27, 2026

2-Phenyl-1,3-thiazole-5-carbaldehyde → 1-(4'-{3-Methyl-4-[(2-phenyl-thiazol-5-ylmethyl)-amino]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1624474

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-1,3-thiazole-5-carbaldehydeHCID 2763706—
Reactant1-[4'-(4-Amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66577195—
Product1-(4'-{3-Methyl-4-[(2-phenyl-thiazol-5-ylmethyl)-amino]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl esterHCID 66577758—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 12, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-phenyl-thiazole-5-carbaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778983B2
Source datasetuspto-grants-2014_07
ORD IDord-cf38f15bf43e40368f85ca92852cf6ca
Source noteuspto-grants-2014_07