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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1624482Generated: October 30, 2026

2-Bromo-6-phenylpyridine → 1-(4'-{4-[Hydroxy-(6-phenyl-pyridin-2-yl)-methyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1624482

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-6-phenylpyridineHCID 568679—
Reactant1-[4'-(4-Formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 86652402—
Product1-(4'-{4-[Hydroxy-(6-phenyl-pyridin-2-yl)-methyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl esterHCID 66577810—

Reaction Steps

Prepared according to the procedure described in Example 34, Step 3, using 1-[4′-(4-formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-bromo-6-phenyl-pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778983B2
Source datasetuspto-grants-2014_07
ORD IDord-70c35e7e4bea417296edd7eec1ecee3e
Source noteuspto-grants-2014_07