3,5-Dibromopyridine → 3-Bromo-5-(3-(trifluoromethyl)phenyl)pyridine

HRID 1624491Notes

Reaction equation

HRID 1624491 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Br:8])[CH:7]=1.[F:9][C:10]([F:21])([F:20])[C:11]1[CH:12]=[C:13](B(O)O)[CH:14]=[CH:15][CH:16]=1>>[Br:8][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([C:15]2[CH:14]=[CH:13][CH:12]=[C:11]([C:10]([F:21])([F:20])[F:9])[CH:16]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 693693,5-DibromopyridineHCID 27343883-(Trifluoromethyl)phenylboronic acid

Product 1

HCID 299195683-Bromo-5-(3-(trifluoromethyl)phenyl)pyridine

Procedure

Prepared according to the procedure described in Example 1, Step 10, using 3,5-dibromo-pyridine and 3-(trifluoromethyl)-phenylboronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ad6a72445692484ba0e04460c319e7ed
Source dataset
uspto-grants-2014_07
Patent number
US08778983B2

Reaction notes

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