3,5-Dibromopyridine → 3-Bromo-5-[4-(trifluoromethyl)phenyl]pyridine

HRID 1624493Notes

Reaction equation

HRID 1624493 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Br:8])[CH:7]=1.[F:9][C:10]([F:21])([F:20])[C:11]1[CH:16]=[CH:15][C:14](B(O)O)=[CH:13][CH:12]=1>>[Br:8][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([C:14]2[CH:15]=[CH:16][C:11]([C:10]([F:21])([F:20])[F:9])=[CH:12][CH:13]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 693693,5-DibromopyridineHCID 27343894-(Trifluoromethyl)phenylboronic acid

Product 1

HCID 665206043-Bromo-5-[4-(trifluoromethyl)phenyl]pyridine

Procedure

Prepared according to the procedure described in Example 1, Step 10, using 3,5-dibromo-pyridine and 4-(trifluoromethyl)-phenylboronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-8a707412ab8e43c486465c70277de1f2
Source dataset
uspto-grants-2014_07
Patent number
US08778983B2

Reaction notes

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