2-Bromo-6-phenylpyridine → HCID 66577710, compound

HRID 1624496Notes

Reaction equation

HRID 1624496 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][C:19]([C:22]4[O:26][N:25]=[C:24]([CH3:27])[C:23]=4[NH2:28])=[CH:18][CH:17]=3)=[CH:12][CH:11]=2)[CH2:9][CH2:8][CH2:7]1)=[O:5])[CH3:2].Br[C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)[N:31]=1>>[CH2:1]([O:3][C:4]([C:6]1([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][C:19]([C:22]4[O:26][N:25]=[C:24]([CH3:27])[C:23]=4[NH:28][C:30]4[CH:35]=[CH:34][CH:33]=[C:32]([C:36]5[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=5)[N:31]=4)=[CH:18][CH:17]=3)=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH2:9]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 5686792-Bromo-6-phenylpyridineHCID 66577807HCID 66577807, compound

Product 1

HCID 66577710HCID 66577710, compound

Procedure

Prepared according to the procedure described in Example 41, Step 2, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclobutanecarboxylic acid ethyl ester and 2-bromo-6-phenyl-pyridine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-585accbd59de489d8d5b0e92b4fb4e9e
Source dataset
uspto-grants-2014_07
Patent number
US08778983B2

Reaction notes

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