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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1624497Generated: October 31, 2026

3-Bromo-5-phenylpyridine → 1-(4'-{4-[Hydroxy-(5-phenyl-pyridin-3-yl)-methyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1624497

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-phenylpyridineHCID 2762904—
Reactant1-[4'-(4-Formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 86652402—
Product1-(4'-{4-[Hydroxy-(5-phenyl-pyridin-3-yl)-methyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl esterHCID 66577714—

Reaction Steps

Prepared according to the procedure described in Example 19, Step 1, using 1-[4′-(4-formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 3-bromo-5-phenyl-pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778983B2
Source datasetuspto-grants-2014_07
ORD IDord-fdb7f6e931694345ae7391b70c543a3f
Source noteuspto-grants-2014_07