HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichlorobenzeneboronic acid → HCID 66577676, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichlorobenzeneboronic acid | HCID 2734332 | — |
| Reactant | 1-(4'-{3-Methyl-4-[6-bromo-pyridin-2-ylamino]-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid ethyl ester | HCID 86652417 | — |
| Catalyst | Bis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloropalladium;iron(2+) | HCID 178418228 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | HCID 66577676 | HCID 66577676 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 10, using 1-{4′-[4-(6-bromo-pyridin-2-ylamino)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester and 2,6-dichloro-phenylboronic acid. Additionally, (1,1′-bis(diphenylphosphino)ferrocene)-dichloropalladium(II) was used as the catalyst in place of tetrakis(triphenylphosphine)palladium(0).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778983B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-6d5e8e322a2e40f7a3ece7c6dd5fbfb5 |
| Source note | uspto-grants-2014_07 |