HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dibromopyridine → 3-Bromo-5-(2-chloro-3-fluorophenyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dibromopyridine | HCID 69369 | — |
| Reactant | (2-Chloro-3-fluorophenyl)boronic acid | HCID 22309459 | — |
| Catalyst | Bis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloropalladium;iron(2+) | HCID 178418228 | — |
| Product | 3-Bromo-5-(2-chloro-3-fluorophenyl)pyridine | HCID 66577777 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 10, using 3,5-dibromo-pyridine and 2-chloro-3-fluoro-phenylboronic acid. (1,1′-bis(diphenylphosphino)ferrocene)-dichloropalladium(II) was used in place of tetrakis(triphenylphosphine)palladium(0).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778983B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-f6233add8a634374b365c2b0725b9551 |
| Source note | uspto-grants-2014_07 |