HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl (5-(4-bromophenyl)-3-methylisoxazol-4-yl)carbamate → {5-[4'-(1-Methanesulfonylaminocarbonyl-cyclopropyl)-biphenyl-4-yl]-3-methyl-isoxazol-4-yl}-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl (5-(4-bromophenyl)-3-methylisoxazol-4-yl)carbamate | HCID 66577242 | — |
| Reactant | N-{1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropanecarbonyl}-methanesulfonamide | HCID 66577823 | — |
| Product | {5-[4'-(1-Methanesulfonylaminocarbonyl-cyclopropyl)-biphenyl-4-yl]-3-methyl-isoxazol-4-yl}-carbamic acid tert-butyl ester | HCID 66577855 | — |
Reaction Steps
Prepared according to the procedure described in Example 94, Step 3, using [5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-carbamic acid tert-butyl ester and N-{1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropanecarbonyl}-methanesulfonamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778983B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-938852125e9c4e3396a39270a3e1ca69 |
| Source note | uspto-grants-2014_07 |