2-Bromo-6-phenylpyridine → HCID 66577632, compound

HRID 1624530Notes

Reaction equation

HRID 1624530 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH2:26][CH3:27])[C:22]=4[NH2:28])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].Br[C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)[N:31]=1>>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH2:26][CH3:27])[C:22]=4[NH:28][C:30]4[CH:35]=[CH:34][CH:33]=[C:32]([C:36]5[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=5)[N:31]=4)=[CH:17][CH:16]=3)=[CH:13][CH:14]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 5686792-Bromo-6-phenylpyridineHCID 66577755HCID 66577755, compound

Product 1

HCID 66577632HCID 66577632, compound

Procedure

Prepared according to the procedure described in Example 41, Step 2, using 1-[4′-(4-amino-3-ethyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-bromo-6-phenyl-pyridine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-66d9f44527cf4817908fe14dce298032
Source dataset
uspto-grants-2014_07
Patent number
US08778983B2

Reaction notes

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