Tetrahydrofuran → HCID 58270444, compound

Participants

Reaction Steps

2-(4-Fluorobenzyl)-5-nitroisoquinolin-1(2H)-one (0.66 g, 0.0022 mol) and tin dichloride dihydrate (2 g, 0.009 mol) were stirred in tetrahydrofuran (20 mL, 0.2 mol) at room temperature overnight. The volatiles were removed via rotovapor, and the residue was dissolved in MeOH, filter through a pad of basic alumina and concentrated to dryness to give the title compound as a brown oil. MS m/z (M+H) 268.8.

Provenance & Evidence