反应详情

5-Nitro-isochromen-1-one (1.0 g, 0.0052 mol) and C-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-methylamine (1.0 g, 0.0060 mol) were refluxed in methanol (40 mL, 1 mol) for 2 hours. The solvent was removed and the residue was purified via flash chromatography (40 g of silica gel, 0-30% EtOAc/Hexanes) gave a yellow solid.

1. customThe solvent was removed
2. customthe residue was purified via flash chromatography (40 g of silica gel, 0-30% EtOAc/Hexanes)
3. customgave a yellow solid