HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 58270428, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1,3-Dioxolane-4-methanamine, 2,2-dimethyl- | HCID 4122349 | — |
| Reactant | 5-nitro-1H-isochromen-1-one | HCID 10012760 | — |
| Product | HCID 58270428 | HCID 58270428 | — |
Reaction Steps
5-Nitro-isochromen-1-one (8 g, 0.04 mol) and (2,2-dimethyl-1,3-dioxolan-4-yl)methanamine (5 g, 0.04 mol) were refluxed in methanol (40 mL, 1 mol) for 2 hours. The volatiles were removed via rotovapor, and the residue was purified via flash column chromatography (330 g of silica gel, 0-50% EtOAc/Hexane) to give a bright yellow solids.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08779144B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-a39e1a0a3e1d4e6c8e94d8d32084d7e0 |
| Source note | uspto-grants-2014_07 |