Ethanol → HCID 59411435, compound

HRID 1624997Notes

Reaction equation

HRID 1624997 reaction equation
[C:1]([O:4][CH2:5][CH:6]([N:12]1[CH:21]=[CH:20][C:19]2[C:14](=[CH:15][CH:16]=[CH:17][C:18]=2[N+:22]([O-])=O)[C:13]1=[O:25])[CH2:7][O:8][C:9](=[O:11])[CH3:10])(=[O:3])[CH3:2].C(O)C>[Pd]>[C:9]([O:8][CH2:7][CH:6]([N:12]1[CH:21]=[CH:20][C:19]2[C:14](=[CH:15][CH:16]=[CH:17][C:18]=2[NH2:22])[C:13]1=[O:25])[CH2:5][O:4][C:1](=[O:3])[CH3:2])(=[O:11])[CH3:10]

Participants

4

Reactant 2

HCID 702EthanolHCID 59411458HCID 59411458, compound

Product 1

HCID 59411435HCID 59411435, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

2-(5-Nitro-1-oxoisoquinolin-2(1H)-yl)propane-1,3-diyl diacetate (6.3 g, 0.018 mol) was stirred with palladium 10% wt. on calcium carbonate (0.6 g, 0.003 mol) in ethanol (100 mL, 2 mol) under hydrogen (balloon) over 1 h at room temperature. The catalyst was filtered, the filtrate was concentrated to dryness to give a yellow oil. MS m/z (M+H) 319.2

Workup

  1. filtrationThe catalyst was filtered
  2. concentrationthe filtrate was concentrated to dryness
  3. customto give a yellow oil

Sources & evidence

ORD record
ord-fc81505100364bc9a1a917ebc49cae08
Source dataset
uspto-grants-2014_07
Patent number
US08779144B2

Reaction notes

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