HCID 58481118, compound → HCID 67365667, compound

Participants

Reaction Steps

3-(4-acetyl-3-nitrophenyl)-2-aminopropanoic acid was reduced by 5% Pd on carbon in MeOH under 1 atm H2. Filtration followed by concentration under reduced pressure afforded 3-(4-Acetyl-3-aminophenyl)-2-aminopropanoic acid (X3179-96). MS (ESI+): m/z 223.22 (MH+). 1H NMR (400 MHz, MeOD): δ 7.78 (d, J=8.4 Hz, 1H), 6.66 (s, 1H), 6.54 (d, J=8.4 Hz, 1H), 4.25 (dd, J′=8.4 Hz, J″=5.2 Hz, 1H), 3.23 (dd, J′=14.4 Hz, J″=5.2 Hz, 1H), 3.02 (dd, J′=14.4 Hz, J″=8.4 Hz, 1H), 2.54 (s, 3H); 13C NMR: δ 202.14, 171.20, 152.93, 142.51, 134.40, 118.78, 118.23, 116.91, 54.63, 37.42, 27.90.

Provenance & Evidence