HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Tributylstannyl)pyrimidine → 1-(beta-D-glucopyranosyl)-4-methyl-3-(5-(2-pyrimidinyl)-2-thienylmethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Tributylstannyl)pyrimidine | HCID 2763251 | — |
| Reactant | 1-(4-ethylbenzyl)-5-bromopyridin-2(1H)-one | HCID 58242500 | — |
| Reactant | 1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-3-(5-bromo-2-thienylmethyl)-4-methylbenzene | HCID 66607903 | — |
| Product | 1-(beta-D-glucopyranosyl)-4-methyl-3-(5-(2-pyrimidinyl)-2-thienylmethyl)benzene | HCID 11304922 | — |
Reaction Steps
1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-3-(5-bromo-2-thienylmethyl)-4-methylbenzene obtained in Example 159-(1) and tri-n-butyl(2-pyrimidinyl)tin 54 were treated in a manner similar to Example 128-(5) and (6) to give the target compound. APCI-Mass m/Z 429 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785403B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-733e0a66d0c54d64879098e4ba6e9405 |
| Source note | uspto-grants-2014_07 |