HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-((Phenylmethoxy)methyl)-5-(tributylstannyl)-2H-tetrazole → 1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-3-(5-(2-benzyloxymethyl-2H-tetrazol-5-yl)-2-thienylmethyl)-4-chlorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-((Phenylmethoxy)methyl)-5-(tributylstannyl)-2H-tetrazole | HCID 11340561 | — |
| Reactant | 1-(2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl)-3-(5bromo-2-thienylmethyl)-4-chlorobenzene | HCID 60041289 | — |
| Product | 1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-3-(5-(2-benzyloxymethyl-2H-tetrazol-5-yl)-2-thienylmethyl)-4-chlorobenzene | HCID 66607043 | — |
Reaction Steps
1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-3-(5bromo-2-thienylmethyl)-4-chlorobenzene obtained in Example 128-(4) and (2-benzyloxymethyl-2H-tetrazol-5-yl)trin-butyltin (see Tetrahedron Lett. (2000) 2805) were treated in a manner similar to Example 128-(5) to give 1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-3-(5-(2-benzyloxymethyl-2H-tetrazol-5-yl)-2-thienylmethyl)-4-chlorobenzene as colorless solid. APCI-Mass m/Z 727/729 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785403B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-3356963e809d4e75ab81a702597f1ea1 |
| Source note | uspto-grants-2014_07 |