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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1625801Generated: November 1, 2026

1-Benzothiophene-2-carbaldehyde → 2-(4-Bromo-1-methoxynaphthalen-2-yl-methyl)benzo[b]thiophene

https://huagongshe.com/reaction/1625801

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzothiophene-2-carbaldehydeHCID 736500—
Reactant2,4-Dibromo-1-methoxynaphthaleneHCID 3572059—
Product2-(4-Bromo-1-methoxynaphthalen-2-yl-methyl)benzo[b]thiopheneHCID 66608193—

Reaction Steps

2,4-Dibromo-1-methoxynaphthalene (see J. Clayden, et al. Org. Lett., 5, (2003) 831) and benzo[b]thiophene-2-carboxaldehyde were treated in a manner similar to Reference Example 1 to give the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08785403B2
Source datasetuspto-grants-2014_07
ORD IDord-836a550d1efe4ac1beb2ed7464993f0c
Source noteuspto-grants-2014_07