5-Bromo-2-chlorobenzaldehyde → HCID 66608092, compound

HRID 1625811Notes

Reaction equation

HRID 1625811 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[CH:9]=[CH:8][S:7][C:6]=2[CH:10]=1.[Br:11][C:12]1[CH:13]=[CH:14][C:15]([Cl:20])=[C:16]([CH:19]=1)[CH:17]=O>>[Br:11][C:12]1[CH:13]=[CH:14][C:15]([Cl:20])=[C:16]([CH2:17][C:8]2[S:7][C:6]3[CH:10]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=3[CH:9]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 106089255-Bromo-2-chlorobenzaldehydeHCID 123986016-Chloro-1-benzothiophene

Product 1

HCID 66608092HCID 66608092, compound

Procedure

The above 6-chlorobenzo[b]thiophene and 5-bromo-2-chlorobenzaldehyde obtained in Reference Example 16-(1) were treated in a manner similar to Reference Example 7 to give 5-bromo-2-chloro-1-(6-chlorobenzo[b]thiophen-2-ylmethyl)benzene as colorless crystals.

Workup

  1. additionwere treated in a manner similar to Reference Example 7

Sources & evidence

ORD record
ord-c0240366b91248ef89c9a2511f95867e
Source dataset
uspto-grants-2014_07
Patent number
US08785403B2

Reaction notes

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