5-Bromo-2-chlorobenzaldehyde → HCID 66607743, compound

HRID 1625823Notes

Reaction equation

HRID 1625823 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([C:10]2[S:11][CH:12]=[CH:13][CH:14]=2)[CH:7]=[CH:8][CH:9]=1)[CH3:2].[Br:15][C:16]1[CH:17]=[CH:18][C:19]([Cl:24])=[C:20]([CH:23]=1)[CH:21]=O>>[Br:15][C:16]1[CH:17]=[CH:18][C:19]([Cl:24])=[C:20]([CH2:21][C:12]2[S:11][C:10]([C:6]3[CH:7]=[CH:8][CH:9]=[C:4]([O:3][CH2:1][CH3:2])[CH:5]=3)=[CH:14][CH:13]=2)[CH:23]=1

Participants

3

Reactant 2

HCID 106089255-Bromo-2-chlorobenzaldehydeHCID 66608066HCID 66608066, compound

Product 1

HCID 66607743HCID 66607743, compound

Procedure

The above 2-(3-ethoxyphenyl)thiophene and 5-bromo-2-chlorobenzaldehyde obtained in Reference Example 16-(1) were treated in a manner similar to Reference Example 9 to give 5-bromo-2-chloro-1-(5-(3-ethoxyphenyl)-2-thienylmethyl)benzene as colorless oil. APCI-Mass m/Z 407/409 (M+H).

Workup

  1. additionwere treated in a manner similar to Reference Example 9

Sources & evidence

ORD record
ord-e569ca8e5ad247ed9cb72b63a39bebd9
Source dataset
uspto-grants-2014_07
Patent number
US08785403B2

Reaction notes

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