5-Bromo-2-fluorobenzaldehyde → HCID 66607479, compound

HRID 1625827Notes

Reaction equation

HRID 1625827 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[S:11][CH:12]=[CH:13][CH:14]=2)=[CH:6][CH:5]=1)[CH3:2].[Br:15][C:16]1[CH:17]=[CH:18][C:19]([F:24])=[C:20]([CH:23]=1)[CH:21]=O>>[Br:15][C:16]1[CH:17]=[CH:18][C:19]([F:24])=[C:20]([CH2:21][C:12]2[S:11][C:10]([C:7]3[CH:8]=[CH:9][C:4]([O:3][CH2:1][CH3:2])=[CH:5][CH:6]=3)=[CH:14][CH:13]=2)[CH:23]=1

Participants

3

Reactant 2

HCID 7363275-Bromo-2-fluorobenzaldehydeHCID 18387525HCID 18387525, compound

Product 1

HCID 66607479HCID 66607479, compound

Procedure

2-(4-Ethoxyphenyl)thiophene obtained in Reference Example 68-(1) and 5-bromo-2-fluorobenzaldehyde were treated in a manner similar to Reference Example 7 to give the target compound. APCI-Mass m/Z 391/393 (M+H).

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-cdc3d24f768d4f898201707b9a78ecc2
Source dataset
uspto-grants-2014_07
Patent number
US08785403B2

Reaction notes

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