2-Thiopheneboronic acid → HCID 18387839, compound

HRID 1625868Notes

Reaction equation

HRID 1625868 reaction equation
Br[C:2]1[CH:10]=[CH:9][C:5]2[O:6][CH2:7][CH2:8][C:4]=2[CH:3]=1.[S:11]1[CH:15]=[CH:14][CH:13]=[C:12]1B(O)O>>[O:6]1[CH2:7][CH2:8][C:4]2[CH:3]=[C:2]([C:12]3[S:11][CH:15]=[CH:14][CH:13]=3)[CH:10]=[CH:9][C:5]1=2

Participants

3

Reactant 2

HCID 27339602-Thiopheneboronic acidHCID 27761595-Bromo-2,3-dihydro-1-benzofuran

Product 1

HCID 18387839HCID 18387839, compound

Procedure

The above 5-bromo-2,3-dihydrobenzo[b]furan and thiophene-2-boronic acid were treated in a manner similar to Reference Example 20-(1) to give the desired 2-(2,3-dihydro-5-benzo[b]furanyl)thiophene as pale yellow crystals. APCI-Mass m/Z 203 (M+H).

Sources & evidence

ORD record
ord-408bc8e27d4842d79dddc50b3ca53928
Source dataset
uspto-grants-2014_07
Patent number
US08785403B2

Reaction notes

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