2-Fluoroethyl bromide → HCID 86601080, compound

HRID 1625909Notes

Reaction equation

HRID 1625909 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:19])=[C:6]([CH2:8][C:9]2[S:13][C:12]3[CH:14]=[CH:15][C:16]([OH:18])=[CH:17][C:11]=3[CH:10]=2)[CH:7]=1.Br[CH2:21][CH2:22][F:23]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:19])=[C:6]([CH2:8][C:9]2[S:13][C:12]3[CH:14]=[CH:15][C:16]([O:18][CH2:21][CH2:22][F:23])=[CH:17][C:11]=3[CH:10]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 129822-Fluoroethyl bromideHCID 66607417HCID 66607417, compound

Product 1

HCID 86601080HCID 86601080, compound

Procedure

The above 5-bromo-1-(5-hydroxybenzo[b]thiophen-2-yl-methyl)-2-methylbenzene and 1-bromo-2-fluoroethane were treated in a manner similar to Reference Example 132-(2) to give the desired 5-bromo-1-(5-(2-fluoroethyloxy)-benzo[b]thiophene-2-ylmethyl)-2-methylbenzene.

Sources & evidence

ORD record
ord-c2ad6f619fec4650a8f347f921b89746
Source dataset
uspto-grants-2014_07
Patent number
US08785403B2

Reaction notes

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