Allyl Alcohol → HCID 12384091, compound

HRID 1626015Notes

Reaction equation

HRID 1626015 reaction equation
[CH2:1]([OH:4])[CH:2]=[CH2:3].[CH2:5]([C@@H:7]1[O:9][CH2:8]1)[Cl:6]>C(OCC)C>[CH2:1]([O:4][CH2:8][C@@H:7]([OH:9])[CH2:5][Cl:6])[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 7858Allyl AlcoholHCID 2734062(-)-Epichlorohydrin

Product 1

HCID 12384091HCID 12384091, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Conditions

Temperature
45 °C

Procedure

A boron trifluoride-diethyl ether complex (0.34 ml) was added to allyl alcohol (11 ml), and the mixture was warmed to 45° C. Then, (R)-epichlorohydrin (5.0 g) was added and the mixture was stirred at the same temperature for 1.5 hours. Diethyl ether was added, followed by washing with water and drying over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give the crude title compound (10 g).

Workup

  1. washby washing with water
  2. dry with materialdrying over anhydrous magnesium sulfate
  3. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-23cfe93d90024a23b5d4c7cf819ad688
Source dataset
uspto-grants-2014_07
Patent number
US08785438B2

Reaction notes

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