HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 67325418, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Aminotetrahydropyran hydrochloride | HCID 44118693 | — |
| Reactant | HCID 67175734 | HCID 67175734 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67325418 | HCID 67325418 | 20.7% |
Reaction Steps
A mixture of 100 mg of 5-methanesulfonyl-7-propoxy-2-(3-methyl-phenyl)-oxazolo[5,4-d]pyrimidine, 40 mg of 4-aminotetrahydropyran hydrochloride and 39 μl of triethylamine in 3 ml of DMF was heated for 8 h to 50° C. After filtration, the solvent was distilled off in vacuo, and the product was isolated via preparative HPLC to yield 22 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785439B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-3e1152d070d64fe69cfc9bf52c7420b3 |
| Source note | uspto-grants-2014_07 |