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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1626024Generated: November 2, 2026

Cesium carbonate → HCID 67324778, compound

https://huagongshe.com/reaction/1626024

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCesium carbonateHCID 10796—
ReactantHCID 67175734HCID 67175734—
ReactantHCID 178527881HCID 178527881—
SolventDimethylformamideHCID 6228—
ProductHCID 67324778HCID 6732477812.6%

Reaction Conditions

Temperature100 °C

Reaction Steps

113 mg of cesium carbonate and 100 mg of 5-methanesulfonyl-7-propoxy-2-(3-methyl-phenyl)-oxazolo[5,4-d]pyrimidine were added to a solution of 34 mg of 2-mercaptothiazole in 3 ml of DMF. The mixture was heated to 100° C. in a microwave reactor for 15 min. After cooling and filtration, the solvent was distilled off in vacuo, and the product was isolated via preparative HPLC to yield 14 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08785439B2
Source datasetuspto-grants-2014_07
ORD IDord-22ade318db65446fb3212231be50c636
Source noteuspto-grants-2014_07