(Pyrimidin-5-yl)boronic acid → HCID 71009090, compound

Participants

Reaction Steps

In a manner analogous to that described in Example 31, the cross-coupling reaction of (R)-4-(5-bromo-2,4-difluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate A6.2) and pyrimidin-5-ylboronic acid yielded the title compound as a yellow solid. MS (ISP): m/z=341.1 [M+H]+.

Provenance & Evidence