5-Chloropyridine-3-boronic acid → HCID 71008451, compound

Participants

Reaction Steps

In a manner analogous to that described in Example 31, the cross-coupling reaction of 4-(5-bromo-2-fluorophenyl)-4-(difluoromethyl)-5,6-dihydro-4H-1,3-oxazin-2-amine (intermediate A6.12) and 5-chloropyridin-3-ylboronic acid yielded the title compound as a light brown solid. MS (ISP): m/z=356.0 [M+H]+ and 358.0 [M+2+H]+.

Provenance & Evidence