HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 66928654, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(Bromomethyl)pyridine hydrobromide | HCID 2734720 | — |
| Reactant | 2-(2-Methyl-2H-pyrazol-3-yl)-4-nitrophenol | HCID 135697935 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 66928654 | HCID 66928654 | 110.7% |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A mixture of 2-(2-methyl-2H-pyrazol-3-yl)-4-nitro-phenol (100 mg, 0.46 mmol), 2-bromomethylpyridine hydrobromide salt (140 mg, 0.55 mmol) and potassium carbonate (158 mg, 1.15 mmol) in DMSO (4 mL) was stirred at 100° C. overnight. The crude was purified by HPLC to provide the title compound as a brown solid (158 mg, 81%). Exact mass calculated for C16H14N4O3 310.1, found 311.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785441B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-b2d6bb19495b45b490e93e805236587d |
| Source note | uspto-grants-2014_07 |