Chloroform → HCID 178436799, compound

HRID 1626266Notes

Reaction equation

HRID 1626266 reaction equation
O.[I-:2].[I-].[I-].[I-].[CH2:6]([C:8]1[CH:9]=[CH:10][CH:11]=[C:12]2[C:21]=1[N:20]=[C:19]1[C:14]([CH:15]=[CH:16][CH:17]=[C:18]1[CH3:22])=[S+:13]2)[CH3:7].[CH2:23]([C:25]1[CH:26]=[CH:27][CH:28]=[C:29]2[C:38]=1[N:37]=[C:36]1[C:31]([CH:32]=[CH:33][CH:34]=[C:35]1[CH3:39])=[S+:30]2)[CH3:24].[CH2:40]([C:42]1[CH:43]=[CH:44][CH:45]=[C:46]2[C:55]=1[N:54]=[C:53]1[C:48]([CH:49]=[CH:50][CH:51]=[C:52]1[CH3:56])=[S+:47]2)[CH3:41].C(C1C=CC=C2[C:72]=1[N:71]=[C:70]1C(C=CC=C1C)=[S+]2)C.C(Cl)(Cl)Cl>>[I-:2].[I-:2].[I-:2].[CH3:36][N:37]([CH3:38])[C:10]1[CH:9]=[C:8]([CH2:6][CH3:7])[C:21]2[C:12]([CH:11]=1)=[S+:13][C:14]1[C:19](=[C:18]([CH3:22])[CH:17]=[CH:16][CH:15]=1)[N:20]=2.[CH3:70][N:71]([C:44]1[CH:43]=[C:42]([CH2:40][CH3:41])[C:55]2[C:46]([CH:45]=1)=[S+:47][C:48]1[C:53](=[C:52]([CH3:56])[CH:51]=[CH:50][CH:49]=1)[N:54]=2)[CH3:72].[CH3:19][N:20]([C:27]1[CH:26]=[C:25]([CH2:23][CH3:24])[C:38]2[C:29]([CH:28]=1)=[S+:30][C:31]1[C:36](=[C:35]([CH3:39])[CH:34]=[CH:33][CH:32]=1)[N:37]=2)[CH3:21]

Participants

3

Reactant 2

HCID 6212ChloroformHCID 866670301-Ethyl-9-methylphenothiazin-5-ium tetraiodide hydrate

Product 1

HCID 178436799HCID 178436799, compound

Procedure

To the stirred mixture of 9-ethyl-1-methylphenothiazin-5-ium tetraiodide hydrate (383 mg, 0.5 mmol) in anhydrous CHCl3 (20 mL) dimethylamine (0.5 mL, 1.0 mmol, 2 M solution in THF) was added drop wise over 4 h. The resulting mixture was stirred at room temperature overnight, concentrated to dryness.

Workup

  1. additionwas added drop wise over 4 h
  2. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-7dca0e0c7a7e490581fb7320c70673c3
Source dataset
uspto-grants-2014_07
Patent number
US08785434B2

Reaction notes

Loading…