Hexane → HCID 67287835, compound

Participants

Reaction Conditions

Reaction Steps

6-Chloro-7-(4-(6-chloroquinolin-2-ylcarbamoyl)phenoxy)chroman-4-carboxylic acid (0.050 g, 0.098 mmol) in THF (1.5 mL) was heated until a homogeneous solution resulted. The reaction was filtered and sodium 2-ethylhexanoate (0.020 g, 0.12 mmol) was added. The reaction was cooled to 0° C. Hexane was added in 0.5 mL portions and the solution was stored in the freezer overnight. The resulting solids were collected by filtration and dried to provide the desired product (0.043 g, 0.081 mmol, 82% yield). MS (ESI)=509.1 (M+1).

Provenance & Evidence