Methanol → HCID 67288093, compound

Participants

Reaction Steps

To a solution of 6-chloro-7-(4-(6′-methoxy-2,3′-bipyridin-6-ylcarbamoyl)phenoxy)chroman-4-carboxylic acid (0.080 g, 0.150 mmol) in 1:1 THF/methanol (2 ml) was added a 0.5 M solution of sodium methoxide in methanol (0.301 ml, 0.150 mmol), and the reaction was stirred for 2 hours, then concentrated to yield the desired compound (0.080 g, 0.144 mmol, 96.0% yield). MS (apci) m/z=532.2 (M-Na+2H).

Provenance & Evidence