Methanol → HCID 67287900, compound

Participants

Reaction Steps

To a solution of 6-chloro-7-(4-(6′-methoxy-3,3′-bipyridin-6-ylcarbamoyl)phenoxy)chroman-4-carboxylic acid (0.040 g, 0.0752 mmol) in 1:1 THF/MeOH (2 ml) was added a 0.5M solution of sodium methoxide in methanol (0.150 ml, 0.0752 mmol), and the reaction was stirred for 2 hours at ambient temperature. The reaction was concentrated to yield the desired compound (0.040 g, 0.0722 mmol, 96.0% yield). MS (apci) m/z=532.2 (M-Na+2H).

Provenance & Evidence