Hydrochloric Acid → HCID 67287365, compound

Participants

Reaction Steps

N-(1,3-dioxopropan-2-yl)benzamide (1 g, 5.2 mmol) and (3-chlorophenyl)hydrazine hydrochloride (0.94 g, 5.2 mmol) were mixed with 1N HCl (5 mL), ethanol (40 mL) and concentrated HCl was added (1 mL). The reaction was heated to boiling for 10 minutes and then allowed to cool. The solvent was removed by rotary evaporation. To the resulting residue was added water (20 mL) and dilute ammonium hydroxide (10%) to pH 11. The solids were collected by filtration and washed with water, then dried under vacuum to provide the title compound (1.34 g, 88%).

Provenance & Evidence