N-Cyclopropyl-N'-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea → HCID 66687168, compound

HRID 1626547Notes

Reaction equation

HRID 1626547 reaction equation
[CH2:1]([NH:3][C:4](=[O:36])[NH:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]([N:29]3[CH2:34][CH2:33][O:32][CH2:31][C@@H:30]3[CH3:35])[C:15]3[CH2:21][CH2:20][N:19]([C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[CH2:18][C:16]=3[N:17]=2)=[CH:8][CH:7]=1)[CH3:2].[CH:37]1(NC(NC2C=CC(B3OC(C)(C)C(C)(C)O3)=CC=2)=O)CC1>>[CH:1]1([NH:3][C:4](=[O:36])[NH:5][C:6]2[CH:11]=[CH:10][C:9]([C:12]3[N:13]=[C:14]([N:29]4[CH2:34][CH2:33][O:32][CH2:31][CH:30]4[CH3:35])[C:15]4[CH2:21][CH2:20][N:19]([C:22]([O:24][C:25]([CH3:28])([CH3:26])[CH3:27])=[O:23])[CH2:18][C:16]=4[N:17]=3)=[CH:8][CH:7]=2)[CH2:37][CH2:2]1

Participants

3

Reactant 2

HCID 44119149N-Cyclopropyl-N'-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ureaHCID 59239149HCID 59239149, compound

Product 1

HCID 66687168HCID 66687168, compound

Procedure

Method as described for intermediate 5 using 1-cyclopropyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea.

Sources & evidence

ORD record
ord-c7dd53a2b07d4b299943d869e01a1e28
Source dataset
uspto-grants-2014_07
Patent number
US08785457B2

Reaction notes

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