Ethyl isocyanate → HCID 44816464, compound

HRID 1626595Notes

Reaction equation

HRID 1626595 reaction equation
[CH2:1]([NH:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[N:14]=[C:15]([N:22]3[CH2:27][CH2:26][O:25][CH2:24][CH2:23]3)[C:16]3[CH2:21][NH:20][CH2:19][C:17]=3[N:18]=2)=[CH:9][CH:8]=1)=[O:5])[CH3:2].[CH2:28]([N:30]=[C:31]=[O:32])[CH3:29]>>[CH2:28]([NH:30][C:31]([N:20]1[CH2:21][C:16]2[C:15]([N:22]3[CH2:23][CH2:24][O:25][CH2:26][CH2:27]3)=[N:14][C:13]([C:10]3[CH:11]=[CH:12][C:7]([NH:6][C:4]([NH:3][CH2:1][CH3:2])=[O:5])=[CH:8][CH:9]=3)=[N:18][C:17]=2[CH2:19]1)=[O:32])[CH3:29]

Participants

3

Reactant 2

HCID 8022Ethyl isocyanateHCID 44816299HCID 44816299, compound

Product 1

HCID 44816464HCID 44816464, compound

Procedure

Method as described for example 33 using 1-ethyl-3-(4-(4-morpholino-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-yl)phenyl)urea (example 14) and ethyl isocyanate as starting materials.

Sources & evidence

ORD record
ord-97d4c074e23644a8bccccbeec4a60c89
Source dataset
uspto-grants-2014_07
Patent number
US08785457B2

Reaction notes

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