Ethyl isocyanate → HCID 46913264, compound

HRID 1626607Notes

Reaction equation

HRID 1626607 reaction equation
[CH2:1]([NH:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[N:14]=[C:15]([N:23]3[CH2:28][CH2:27][O:26][CH2:25][CH2:24]3)[C:16]3[CH2:22][CH2:21][NH:20][CH2:19][C:17]=3[N:18]=2)=[CH:9][CH:8]=1)=[O:5])[CH3:2].[CH2:29]([N:31]=[C:32]=[O:33])[CH3:30]>>[CH2:29]([NH:31][C:32]([N:20]1[CH2:21][CH2:22][C:16]2[C:15]([N:23]3[CH2:24][CH2:25][O:26][CH2:27][CH2:28]3)=[N:14][C:13]([C:10]3[CH:9]=[CH:8][C:7]([NH:6][C:4]([NH:3][CH2:1][CH3:2])=[O:5])=[CH:12][CH:11]=3)=[N:18][C:17]=2[CH2:19]1)=[O:33])[CH3:30]

Participants

3

Reactant 2

HCID 8022Ethyl isocyanateHCID 469130711-Ethyl-3-(4-(4-morpholino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl) phenyl)urea

Product 1

HCID 46913264HCID 46913264, compound

Procedure

Method as example 33 using 1-Ethyl-3-(4-(4-morpholino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea (example 82) and ethyl isocyanate as starting materials.

Sources & evidence

ORD record
ord-644798f53bac4bdf88955024ae96c4e2
Source dataset
uspto-grants-2014_07
Patent number
US08785457B2

Reaction notes

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