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HRID1626622

反应详情

EQUATION

反应方程式

HRID 1626622 的结构方程式

REACTANTS

反应物

2
结构：CCN=C=O
HCID8022

Ethyl isocyanate

C3H5NO

结构：Cc1cc(N)ccc1-c1nc2c(c(N3CCOC[C@@H]3C)n1)CCN(C)C2
HCID66688545

未命名化合物

PRODUCTS

生成物

1
结构：CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)CCN(C)C3)c(C)c1
HCID66679215

未命名化合物

收率 20%

PROCEDURE

实验过程

Method as example 85 using (S)-3-methyl-4-(7-methyl-4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)aniline and ethyl isocyanate as starting materials. The solvent was removed in vacuo and purified by prep HPLC (high pH) yielding the title compound (11.8 mg, 0.027 mmol, 20%).

WORKUP

后处理

  1. customThe solvent was removed in vacuo
  2. custompurified by prep HPLC (high pH)