HCID 22326463, compound → HCID 66679613, compound

HRID 1626735Notes

Reaction equation

HRID 1626735 reaction equation
Cl.[Cl:2][C:3]1[CH:4]=[CH:5][C:6]([NH:13][C:14]([CH:16]2[CH2:21][CH2:20][CH2:19][NH:18][CH2:17]2)=[O:15])=[C:7]([CH:12]=1)[C:8]([O:10][CH3:11])=[O:9].[O:22]1[CH:26]=[CH:25][C:24]([C:27]2[CH:28]=[C:29]([CH2:33][C:34](O)=[O:35])[CH:30]=[CH:31][CH:32]=2)=[CH:23]1>>[Cl:2][C:3]1[CH:4]=[CH:5][C:6]([NH:13][C:14]([CH:16]2[CH2:21][CH2:20][CH2:19][N:18]([C:34](=[O:35])[CH2:33][C:29]3[CH:30]=[CH:31][CH:32]=[C:27]([C:24]4[CH:25]=[CH:26][O:22][CH:23]=4)[CH:28]=3)[CH2:17]2)=[O:15])=[C:7]([CH:12]=1)[C:8]([O:10][CH3:11])=[O:9]

Participants

3

Reactant 2

HCID 22326463HCID 22326463, compoundHCID 66680551HCID 66680551, compound

Product 1

HCID 66679613HCID 66679613, compound

Procedure

Using the same method as in Example 9-(ii), the target methyl 5-chloro-2-{[(1-{[3-(furan-3-yl)phenyl]carbonyl}piperidin-3-yl)carbonyl]amino}benzoate was quantitatively obtained using the methyl 5-chloro-2-[(piperidin-3-ylcarbonyl)amino]benzoate hydrochloride obtained in Example 11-(ii) and [3-(furan-3-yl)phenyl]acetic acid.

Sources & evidence

ORD record
ord-56801bf5614d442ba23d4b900b9c3c25
Source dataset
uspto-grants-2014_07
Patent number
US08785473B2

Reaction notes

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