Ethanol → HCID 46935598, compound

Participants

Reaction Steps

22 mg of 10% Pd—C was added to an ethanol (11 mL)/DMF (1 mL) solution comprising 216 mg (0.54 mmol) of 5-(cyclohex-1-en-1-yl)-2-{[(4-cyclohexylphenyl)carbonyl]amino}benzoic acid obtained in Example 81, and the mixture was stirred under hydrogen atmosphere at room temperature for 72 hours. The reaction mixture was filtered using filter paper, and the filtrate was condensed, thereby giving 195 mg of the target 5-cyclohexyl-2-{[(4-cyclohexylphenyl)carbonyl]amino}benzoic acid (yield: 90%).

Provenance & Evidence