HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66679850, compound → HCID 46935601, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66679850 | HCID 66679850 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 46935601 | HCID 46935601 | 81% |
Reaction Steps
55 mg (0.13 mmol) of 5-(cyclohexylethynyl)-2-{[(4-cyclohexylphenyl)carbonyl]amino}benzoic acid obtained in Example 92 and 55 mg of Pd—C were stirred in ethanol (4 mL) at room temperature for 5 days. Thereafter, the mixture was filtered, and the filtrate was condensed, thereby giving 45 mg of the target 5-(2-cyclohexylethyl)-2-{[(4-cyclohexylphenyl)carbonyl]amino}benzoic acid (yield: 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785473B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-91ac06fe5f804946a968b56179b099a7 |
| Source note | uspto-grants-2014_07 |