HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 2-(4-amino-3-nitrophenyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-amino-3-nitrophenylPropanoic acid | HCID 12226817 | — |
| Solvent | Water | HCID 962 | — |
| Product | Ethyl 2-(4-amino-3-nitrophenyl)propanoate | HCID 15558027 | — |
Reaction Steps
To the flask of 2-(4-Amino-3-nitrophenyl)propanoic acid residue was added EtOH (200 mL) and catalytic amounts of sulfuric acid (1 mL) at room temperature. The reaction mixture was refluxed for 6 hrs then cooled to room temperature. The mixture was diluted with H2O and extracted with EtOAc. The organic layer was dried over MgSO4, filtered, and concentrated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08785474B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-f3ecf76d8428456b9cb7f470982df8ba |
| Source note | uspto-grants-2014_07 |