反应详情

温度

150 °C

A mixture of compounds D3 (3.31 g, 22.19 mmol) and D8 (6.2 g, 21.86 mmol, 72% purity, calculated by 1H-NMR) in EtOH (10 ml) was subjected to microwave heating at 150° C. for 40 min. After cooling to room temperature, the solvent was evaporated in vacuo. The residue thus obtained was treated with Et2O and a solid precipitated out. The solid thus obtained was filtered off, washed with EtOAc and dried in vacuo to yield compound D9 (1 g, 18%).

1. temperatureAfter cooling to room temperature
2. customthe solvent was evaporated in vacuo
3. customThe residue thus obtained
4. customa solid precipitated out
5. customThe solid thus obtained
6. filtrationwas filtered off
7. washwashed with EtOAc
8. customdried in vacuo